Sigmaaldrich offers a number of ticlopidine hydrochloride products. Safety data sheet according to 29cfr19101200 and ghs rev. Page 7 of 9 msds dimethylformamide behaviorcentral nervous system convulsions, muscle weakness and oth er symptoms similar to that of acute ingestion, respiration dyspnea. Product name ticlopidine hydrochloride sigmaaldrich. Material safety data sheet msds hexane section 1 product and company identification product product name. View and buy high purity ticlopidine hydrochloride from tocris bioscience. Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes. Ticlopidine is a thienopyridine which, when metabolized by the body, irreversibly blocks the p2y12 component of the adp receptor on the surface of. Hold eyelids apart and flush eyes with plenty of water for at. However, the results of one study atlast trial suggest that the frequency of stent thrombosis and other adverse ischemic events remains low even when ticlopidine is discontinued after 2 weeks of therapy.
Extreme high moderate low section 1 chemical product and company identification product name tizanidine hcl statement of hazardous nature considered a hazardous substance according to osha 29 cfr 1910. Material safety data sheet of ticlopidine hydrochloride. Federal occupational safety and health administration standard 29 cfr 1910. Chemical product and company identification manufacturer name and.
Safety data sheet tris hydrochloride precautionary. Pdf a novel inhibitor of plasminogen activator inhibitor1 provides. Ticlopidine hydrochloride 53885351 cayman chemical. Ticlid ticlopidine hydrochloride is a platelet aggregation inhibitor used to prevent blood clots after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels. Clonidine hydrochloride safety data sheet supersedes revision. Keep ticlid ticlopidine hcl out of reach of children. If any of these problems are persistent, or if you are concerned. First aid measures description of first aid measures. Pdf inhibition of plasminogen activator inhibitor pai1 is useful to treat several. P270 do not eat, drink or smoke when using this product. Hydrochloric acid, 37% ww safety data sheet according to federal register vol. Sds of ticlopidine hydrochloride, safety data sheets, cas. Ticlopidine hydrochloride analytical standard, for drug analysis. Safety data sheet product name lidocaine hydrochloride.
State equivalent standards, and canadian workplace hazardous materials identification system standards cpr 4. Estrogens suppress a behavioral phenotype in zebrafish mutants of. Sarpogrelate hydrochloride may therefore maintain the cbf at a lower mbp than ticlopidine hydrochloride, even though the mbp reduction is about the same or greater. Ticlopidine hydrochloride hazard statements h302 harmful if swallowed. Ticlopidine c14h14clns cid 5472 structure, chemical names, physical and. Valve protection caps must remain in place unless container is secured with valve outlet piped to use point. This msds has been prepared according to the hazard criteria of the controlled products regulations cpr and the msds contains all of the information required by the cpr. As in any fire, wear a selfcontained breathing apparatus in pressuredemand, mshaniosh approved or equivalent, and full protective. Lithium silicide in contact with hydrogen chloride becomes incandescent.
Material safety data sheet of ticlopidine hydrochloride contains identification of substance and details of the supplier of the safety data sheet. Ticlid ticlopidine hcl should be used only as directed by your doctor. No test data on mobility of the components available. As with most organic solids, fire is possible at elevated temperatures or. Precautionary statements p264 wash contaminated skin thoroughly after handling. Cimetidinepmetabolism of ticlopidine and may qthe risk of toxicity. The objective of the current study was to develop a simple, precise and accurate spectrophometric assay method and validated for determination of ticlopidine hydrochloride in solid pharmaceutical dosage forms. Ticlopidine binds to the p2y12 receptor, preventing changes in the glycoprotein iibiiia conformation and suppressing fibrinogenplatelet binding. Calcium carbide reacts with hydrogen chloride gas with incandescence. Safety data sheet according to federal register vol. Keep in a tightly closed container, stored in a cooled, dry, ventilated area. India veritas house, 70 mint road, fort, mumbai 400 001.
December 15, 2003 sulfuric acid page 3 of 5 eu safety phrases. Material safety data sheet hydrochloric acid section 1 chemical product and company identification msds name. Search results for ticlopidine hydrochloride at sigmaaldrich. Aspirinpotentiates the effect of ticlopidine on platelets concurrent usenotrecommended. Ticlopidine is a first generation thienopyridine adpp2y12 receptor inhibitor that exhibits antithrombotic and cardioprotective activities. Side effects of ticlid ticlopidine hcl, warnings, uses. Ticlopidine hydrochloride is metabo lized extensively by the liver, no intact ticlopidine hydrochloride is detected in the urine. Ticlopidine hydrochloride safety data sheet section 2. The mbp range associated with preservation of cbf depends on a balance between the contractility of resistant cerebral arteries and. The students ttest, welchs ttest and the paired ttest were used. The first generic ticlopidine hydrochloride was fda approved in 1999.
Download product insert pdfdownload safety data sheet sds pdf. It can cause gastrointestinal tract irritation with heartburn, abdominal pain, nausea, vomiting or diarrhea. Identification of the substancemixture and of the companyundertaking 1. Ticlopidine hydrochloride monograph for professionals. A pvalue of hydrochloride n 31 or ticlopidine hydrochloride n 43. In patients receiving an intracoronary stent, following successful stent implantation, ticlopidine therapy may be continued for up to 30 days. However, we make no warranty of merchantability or any other warranty, express or implied, with. Ticlopidine inhibits liver cyp2c19 and cyp2b6 and thus can affect blood levels of medications metabolized by these systems. Hydrogen chloride hcl, nitrogen oxides nox, carbon monoxide co, carbon dioxide co2.
Hydrochloric acid, 10% vv safety data sheet according to federal register vol. Doxorubicin hydrochloride solution for injection 2 mgml. Used to reduce the risk of fatal or nonfatal thrombotic stroke in patients who have had either a previous completed thrombotic stroke or stroke precursors e. Unme tabolized ticlopidine hydrochloride is a minor component in plasma after a single dose, but at steady state, ticlopidine hydrochloride is the major component. Material safety data sheet tizanidine hcl sc200148 hazard alert code key. On sdspage c, pai1 formed a covalent complex with tpa, whereas no pai1tpa.
Ticlopidine hydrochloride is an adenosine diphosphate adp receptor inhibitor against platelet aggregation with ic50 of 2. Ticlopidine hydrochloride supplier cas 53885351 tocris. Uranium phosphide reacts with hydrochloric acid to release spontaneously flammable phosphines. Lidocaine hydrochloride and epinephrine injection 1. Ticlopidine trade name ticlid is an antiplatelet drug in the thienopyridine family which is an. Adobe acrobat reader is required to reliably view, print and comment on pdf documents ticlopidine hydrochloride product citations see how others have used ticlopidine hydrochloride. S26 in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Section 5 fire fighting measures general information. Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans. Identification of the substancemixture and of the companyundertaking.
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